ALIVE Project

TABLE OF TERMS

Diabetes mellitus (DM)

• Diabetes mellitus (DM)
  • ALIVE criteria for diagnosing DM in dogs
  • ALIVE criteria for diagnosing DM in cats
• Subclinical diabetes mellitus in dogs and cats
• Clinical diabetes mellitus in dogs and cats
• Prediabetes
• Etiologic classification of diabetes mellitus
• ALIVE diabetes mellitus characterisation checklists. Canine DM checklist
• ALIVE diabetes mellitus characterisation checklists. Feline DM checklist
• Diabetic ketoacidosis (DKA)
• Diabetic remission
• Treatment goals of diabetes mellitus
• Hypoglycaemia
• Insulin resistance
• ALIVE Diabetic Clinical Score

Cushing’s syndrome

• Cushing’s syndrome
• Hypercortisolism
• Subdiagnostic Cushing’s syndrome
• Classification of Cushing’s Syndrome
  1. Naturally-occurring Cushing’s syndrome
     • ACTH-dependent
       • Pituitary-dependent hypercortisolism (PDH)
       • Ectopic ACTH
       • Subdiagnostic Cushing’s syndrome
     • ACTH-independent
       • Adrenal-dependent hypercortisolism (ADH)
       • Aberrant adrenal receptor expression (ectopic and eutopic)
       • Subdiagnostic Cushing’s syndrome
  2. Iatrogenic Cushing’s Syndrome
• ALIVE goals of treatment of naturally-occurring Cushing’s syndrome
• ALIVE Cushing's Clinical Score

Hypoadrenocorticism

• Hypoadrenocorticism
• Primary hypoadrenocorticism
• Secondary hypoadrenocorticism
• Hyponatremic and/or hyperkalemic hypoadrenocorticism
• Eunatraemic, eukalaemic hypoadrenocorticism
• ALIVE criteria for the diagnosis of glucocorticoid deficiency
• ALIVE criteria for the diagnosis of primary hypoadrenocorticism
• ALIVE criteria for the diagnosis of secondary hypoadrenocorticism
• Critical Illness-Related Corticosteroid Insufficiency (CIRCI)
• Adrenal Crisis, formerly known as Addisonian crisis
• ALIVE goals of acute treatment of an adrenal crisis include correction of
• ALIVE goals of chronic treatment of hypoadrencorticism

General definitions for diagnostic tests for Cushing’s and Hypoadrenocorticism

• Resting cortisol
• Urinary Corticoid: Creatinine Ratio (UCCR)
• Urinary Corticoid: Creatinine Ratio (UCCR) dexamethasone suppression test
• Low-dose dexamethasone suppression test (LDDST)
• High-dose dexamethasone suppression test (HDDST)
• ACTH stimulation test
• Endogenous ACTH concentration (eACTH)
• Adrenal imaging (in the context of differentiating tests)
• Pituitary imaging (in the context of differentiating tests for Cushing’s syndrome)
• Hair and salivary cortisol